Semaglutide is a single peptide (branded under the name Ozempic for type 2 diabetes treatment and Wegovy for weight loss) that increases insulin secretion and acts on centers of the brain to suppress appetite. Semaglutide is part of a medication class called glucagon-like peptide-1 (GLP-1) receptor agonists. When this receptor is activated, it slows down how fast the stomach empties. Slow stomach emptying signals the brain to eat less, helping to manage weight. Taken in conjunction with a healthy diet and exercise, Semaglutide can help you lose weight and keep it off.