Tirzepatide is a double peptide (branded under the name Mounjaro for type 2 diabetes treatment and Zepbound for weight loss) that increases insulin secretion and acts on centers of the brain to suppress appetite. Tirzepatide is classified as a glucagon-like peptide-1 (GLP-1) receptor agonist and glucose-dependent insulinotropic polypeptide (GIP) receptor, two natural incretin hormones. When these receptors are activated, it slows down how fast the stomach empties. Slow stomach emptying signals the brain to eat less, helping to manage weight. Taken in conjunction with a healthy diet and exercise, tirzepatide can help you lose weight and keep it off.